SCHEMBL19862488

SCHEMBL19862488

COc1ccccc1C(=O)COS(=O)(=O)C(F)(F)C(=O)NC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.57
FAAH O00519 5/20 0.57
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
EPHX2 P34913 1/20 0.47
P2RX7 Q99572 1/20 0.47
ALDH1A1 P00352 1/20 0.45
CNR1 P21554 2/20 0.44
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862484 0.86 ALDH1A1 (0.42) CNR2FAAHKMT2AMEN1EPHX2
SCHEMBL19862483 0.84 EPHX2 (0.42) CNR2FAAHKMT2AMEN1EPHX2
SCHEMBL19863273 0.83 FAAH (0.50) CNR2FAAHKMT2AMEN1EPHX2
SCHEMBL19862490 0.81 RAB9A (0.48) CNR2KMT2AMEN1EPHX2ALDH1A1
SCHEMBL19862486 0.81 RAB9A (0.48) CNR2KMT2AMEN1EPHX2ALDH1A1
SCHEMBL19862481 0.79 KCNK3 (0.46) KMT2AMEN1ALDH1A1LMNAHTT
SCHEMBL19865185 0.77 L3MBTL1 (0.47) KMT2AALDH1A1LMNAHTT
SCHEMBL6085774 0.74 CNR2 (1.00) CNR2FAAHKMT2AMEN1EPHX2
SCHEMBL19862670 0.73 SMN1; SMN2 (0.41) KMT2AMEN1ALDH1A1LMNAHTT
SCHEMBL10225020 0.72 FAAH (0.40) CNR2FAAHKMT2AMEN1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9950999-B2 Non-ionic low diffusing photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS PLG, PPARG, PKLR CNR2 2021/4885FAAH 562/4885KMT2A 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.