SCHEMBL19862530

SCHEMBL19862530

Cc1ccsc1C(C)(C)Br

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP2A6 P11509 5/20 0.33
ALOX5 P09917 1/20 0.32
GSK3B P49841 1/20 0.32
RIPK1 Q13546 1/20 0.32
CYP2E1 P05181 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2B6 P20813 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL802210 0.82 PKM (0.38) NPC1PKMRAB9AATML3MBTL1
SCHEMBL3234536 0.80 NPC1 (0.37) NPC1PKMRAB9AATML3MBTL1
SCHEMBL20909675 0.78 NPC1 (0.35) NPC1PKMRAB9AATML3MBTL1
SCHEMBL22733836 0.78 CYP2A6 (0.36) NPC1PKMRAB9AATML3MBTL1
SCHEMBL12161061 0.75 NPC1 (0.37) NPC1PKMRAB9AATML3MBTL1
SCHEMBL13868022 0.75 RIPK1 (0.39) NPC1PKMRAB9AATML3MBTL1
SCHEMBL16254998 0.73 NPC1 (0.36) NPC1PKMRAB9AATML3MBTL1
SCHEMBL21719976 0.72 ESR1 (0.34) NPC1PKMRAB9AATML3MBTL1
SCHEMBL12238628 0.72 ALOX5 (0.34) NPC1PKMRAB9AATML3MBTL1
SCHEMBL10697065 0.72 GSK3B (0.39) NPC1PKMRAB9AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10454034-B2 Hexabenzocoronene-based compound for organic photovoltaic cells CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-10-22 US disclosed
US-20180047906-A1 HEXABENZOCORONENE-BASED COMPOUND FOR ORGANIC PHOTOVOLTAIC CELLS UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR (FR) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454034-B2 Hexabenzocoronene-based compound for organic photovoltaic cells H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PPOX, PAX3 NPC1 3314/4885PKM 1232/4885RAB9A 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.