Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862707 | 0.87 | ELANE (0.49) | ELANEMEN1NPC1KMT2AMAPT | |
| SCHEMBL19862712 | 0.84 | ELANE (0.54) | ELANEGAAMEN1KMT2AMAPT | |
| SCHEMBL19862711 | 0.75 | ELANE (0.53) | ELANEGAAMEN1KMT2AMAPT | |
| SCHEMBL19862709 | 0.72 | ELANE (0.61) | ELANEGAAMEN1KMT2AMAPT | |
| SCHEMBL19862713 | 0.70 | ELANE (0.54) | ELANEMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL19862710 | 0.70 | ELANE (0.46) | ELANEALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL825544 | 0.70 | ELANE (0.71) | ELANEGAAMEN1NPC1KMT2A | |
| SCHEMBL18054738 | 0.69 | ELANE (0.34) | ELANEGAAMEN1NPC1KMT2A | |
| SCHEMBL19862715 | 0.67 | ELANE (0.43) | ELANEMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16406554 | 0.66 | ELANE (0.61) | ELANEGAAMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043066-A1 | MACROINITIATORS FOR HYDROPHILIC COATINGS ON LATEX AND APPLICATIONS THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-02-15 | — | — | US | disclosed |