SCHEMBL19863277

SCHEMBL19863277

CC(=O)C(F)(F)S(=O)(=O)OC(C(=O)c1ccccc1)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
CES1 P23141 3/20 0.36
MDM2 Q00987 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CES2 O00748 2/20 0.34
LMNA P02545 2/20 0.34
PTPN1 P18031 2/20 0.34
MLYCD O95822 1/20 0.34
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 1/20 0.33
PGR P06401 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863256 0.87 SRC (0.41) ALDH1A1CYP3A4L3MBTL1LMNAKMT2A
SCHEMBL19863272 0.79 PDK1 (0.42) ALDH1A1CYP3A4L3MBTL1LMNAKMT2A
SCHEMBL19866621 0.79 HDAC8 (0.38) ALDH1A1MLYCDKMT2APOLBMEN1
SCHEMBL27459557 0.79 CES1 (0.38) ALDH1A1CYP3A4CES1MDM2TDP1
SCHEMBL19862653 0.78 ELANE (0.35) ALDH1A1CYP3A4TDP1MLYCDMAPT
SCHEMBL19862667 0.77 POLB (0.33) ALDH1A1CYP3A4TDP1KMT2APOLB
SCHEMBL19863261 0.77 ELANE (0.35) TDP1MLYCDMAPTNPC1POLB
SCHEMBL3899100 0.76 ALDH1A1 (0.56) ALDH1A1CYP3A4CES1MDM2TDP1
SCHEMBL7630497 0.76 CES1 (0.44) ALDH1A1CYP3A4CES1MDM2TDP1
SCHEMBL19863253 0.75 FAAH (0.47) ALDH1A1KMT2ANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG ALDH1A1 888/4885CYP3A4 554/4885CES1 384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.