SCHEMBL19863256

SCHEMBL19863256

COC(=O)C(F)(F)S(=O)(=O)OC(C(=O)c1ccccc1)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.41
MAPK1 P28482 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KCNN4 O15554 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 2/20 0.37
CTRB1 P17538 6/20 0.36
PRSS1 P07477 5/20 0.36
CTSG P08311 5/20 0.36
CMA1 P23946 5/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 2/20 0.36
HSD17B10 Q99714 1/20 0.36
ELANE P08246 1/20 0.35
ALDH1A1 P00352 3/20 0.35
POLB P06746 2/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863277 0.87 ALDH1A1 (0.39) MAPK1NPC1RAB9AL3MBTL1TSHR
SCHEMBL19863272 0.79 PDK1 (0.42) NPC1RAB9AL3MBTL1ALDH1A1MEN1
SCHEMBL19866621 0.79 HDAC8 (0.38) SMN1; SMN2ALDH1A1POLBMEN1KMT2A
SCHEMBL19863261 0.76 ELANE (0.35) MAPK1NPC1CTRB1PRSS1CTSG
SCHEMBL7630497 0.76 CES1 (0.44) SRCNPC1RAB9AL3MBTL1TSHR
SCHEMBL27459557 0.76 CES1 (0.38) L3MBTL1MAPTALDH1A1LMNACYP3A4
SCHEMBL19863253 0.74 FAAH (0.47) MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL19862669 0.74 PDK1 (0.36) NPC1RAB9AGAATSHRALDH1A1
SCHEMBL19862667 0.74 POLB (0.33) HTTSMN1; SMN2ELANEALDH1A1POLB
SCHEMBL19865867 0.73 ABCC9 (0.43) TSHRHTTSMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG SRC 2889/4885MAPK1 1301/4885NPC1 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.