SCHEMBL19863272

SCHEMBL19863272

O=C(c1ccccc1)C(OS(=O)(=O)C(F)(F)C(=O)Nc1cccc(NC(=O)C(F)(F)S(=O)(=O)OC(C(=O)c2ccccc2)C(F)(F)F)c1)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.42
PDK2 Q15119 1/20 0.42
PDK3 Q15120 1/20 0.42
PDK4 Q16654 1/20 0.42
KCNK3 O14649 9/20 0.41
KCNK9 Q9NPC2 9/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862669 0.83 PDK1 (0.36) PDK1PDK2PDK3PDK4MEN1
SCHEMBL19863277 0.79 ALDH1A1 (0.39) L3MBTL1MEN1KMT2ALMNANPC1
SCHEMBL19863256 0.79 SRC (0.41) L3MBTL1MEN1KMT2ALMNANPC1
SCHEMBL19866621 0.79 HDAC8 (0.38) MEN1KMT2ACA12CA1CA2
SCHEMBL19865868 0.77 ABCC9 (0.38) PDK1PDK2PDK3PDK4L3MBTL1
SCHEMBL19865867 0.75 ABCC9 (0.43) PDK1PDK2PDK3PDK4MEN1
SCHEMBL19863253 0.74 FAAH (0.47) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL19863269 0.71 MEN1 (0.51) KCNK3MEN1KMT2ACA12CA1
SCHEMBL19862667 0.71 POLB (0.33) MEN1KMT2AHPGDNPSR1ALDH1A1
SCHEMBL27459557 0.71 CES1 (0.38) L3MBTL1LMNANPSR1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG PDK1 372/4885PDK2 120/4885PDK3 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.