Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977958 | 0.83 | LPL (0.40) | LPLLIPG | |
| SCHEMBL19865293 | 0.81 | LPL (0.41) | LPLLIPG | |
| SCHEMBL21090587 | 0.78 | LPL (0.35) | LPLLIPG | |
| SCHEMBL5899548 | 0.75 | MAPK9 (0.37) | — | |
| SCHEMBL21090923 | 0.74 | LPL (0.32) | LPLLIPG | |
| SCHEMBL13721740 | 0.73 | L3MBTL1 (0.46) | — | |
| SCHEMBL22084424 | 0.70 | PDE10A (0.38) | — | |
| SCHEMBL823021 | 0.69 | LIPG (0.59) | LPLLIPG | |
| SCHEMBL18354582 | 0.68 | CES2 (0.31) | — | |
| SCHEMBL15650209 | 0.66 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031662-A1 | PYRROLOBENZODIAZEPINE PRODRUGS AND ANTIBODY CONJUGATES THEREOF | GENENTECH, INC. (US) | 2018-02-15 | — | — | WO | disclosed |