Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15831460 | 0.86 | DRD2 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL275331 | 0.84 | LTA4H (0.47) | LTA4HCYP1A2CYP2D6CYP19A1CYP2C19 | |
| SCHEMBL15814847 | 0.84 | TDP1 (0.47) | MEN1KMT2ALTA4HRAB9ANPC1 | |
| SCHEMBL31621061 | 0.84 | APP (0.42) | SMN1; SMN2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL2474081 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23755050 | 0.81 | KEAP1 (0.50) | LTA4H | |
| SCHEMBL19879751 | 0.81 | DUT (0.37) | RAB9ASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL12134842 | 0.81 | NOS1 (0.44) | LTA4H | |
| SCHEMBL663356 | 0.81 | DUT (0.37) | ALDH1A1HSD17B10KDM4ECA12CA1 | |
| SCHEMBL23754946 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2HPGDALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074819-B2 | Benzopyran or thiobenzopyran derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-07-11 | — | — | US | disclosed |