SCHEMBL198852

SCHEMBL198852

[c]1cc[c]c2ncccc12

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 2/20 0.32
TP53 P04637 2/20 0.32
ALOX15 P16050 2/20 0.32
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GMNN O75496 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MMP2 P08253 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MMP9 P14780 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
MMP8 P22894 1/20 0.32
CCR1 P32246 1/20 0.32
THPO P40225 1/20 0.32
MTOR P42345 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449811 0.84
SCHEMBL277687 0.71 NUDT1 (0.32) KDM4EMAPTLMNATP53ALOX15
SCHEMBL19695 0.71 TSHR (0.42) KDM4EMAPTLMNATP53ALOX15
SCHEMBL165149 0.70
SCHEMBL2892994 0.70 PSMD14 (0.43) KDM4EMAPTLMNAHTTSMN1; SMN2
SCHEMBL27504674 0.70 TSHR (0.41) KDM4EMAPTLMNATP53ALOX15
SCHEMBL18594 0.70 ALDH1A1 (0.44) KDM4EMAPTLMNATP53ALOX15
SCHEMBL21831938 0.70 TSHR (0.41) KDM4EMAPTLMNATP53ALOX15
SCHEMBL27643306 0.70 TSHR (0.41) KDM4EMAPTLMNATP53ALOX15
SCHEMBL27380184 0.70 TSHR (0.41) KDM4EMAPTLMNATP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027987-A Liquid crystal compound and liquid crystal device 华为技术有限公司 2024-05-14 CN claimed
CN-115650850-A Nano-oxide surface modifier based on fatty acid and preparation method and application thereof 武汉轻工大学 2023-01-31 CN claimed
US-8501046-B2 Use of rylene derivatives as photosensitizers in solar cells BASF SE (DE) 2013-08-06 US claimed
US-20120283432-A1 USE OF RYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS MAX-PLANCK-GESEL. ZUR FOERDERUNG DER WISSEN. E.V. (DE) 2012-11-08 US claimed
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US claimed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US claimed
US-7772323-B2 Conjugated copolymers, representation and use thereof MERCK PATENT GMBH (DE) 2010-08-10 US claimed
EP-1641894-B1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE MERCK PATENT GMBH (DE) 2009-01-21 EP claimed
EP-1592729-B1 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF MERCK PATENT GMBH (DE) 2008-04-23 EP claimed
EP-1219657-B1 POLYARYLENE AND METHOD FOR PRODUCTION THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2008-03-19 EP claimed
EP-1656407-A2 CONJUGATED COPOLYMERS, REPRESENTATION AND USE THEREOF Covion Organic Semiconductors GmbH (DE) 2006-05-17 EP claimed
EP-1641894-A1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE Covion Organic Semiconductors GmbH (DE) 2006-04-05 EP claimed
US-20060058494-A1 Conjugated polymers containing arylamine units, the representation thereof and the use of the same CONVION ORGANIC SEMICONDUCTORS GMBH INTELLECTUAL PROPERTY GROUP (DE) 2006-03-16 US claimed
EP-1592729-A2 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF Covion Organic Semiconductors GmbH (DE) 2005-11-09 EP claimed
EP-1558662-A2 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME Covion Organic Semiconductors GmbH (DE) 2005-08-03 EP claimed
WO-2005014688-A2 CONJUGATED COPOLYMERS, REPRESENTATION AND USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2005-02-17 WO claimed
WO-2004113468-A1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-12-29 WO claimed
WO-2004070772-A2 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-08-19 WO claimed
WO-2004037887-A2 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-06 WO claimed
US-5367038-A Polyisoquinolinediyls and uses thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 1994-11-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283432-A1 USE OF RYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS NR2E3, NR2E1, NR1D2 KDM4E 1373/4885MAPT 4643/4885LMNA 2818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.