Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | CA6 | P23280 | 5/20 | 0.38 |
| ▸ | CA5A | P35218 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.38 |
| ▸ | CA3 | P07451 | 3/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.33 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1997078 | 0.95 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| Potassium Ion SCHEMBL29653632 | 0.95 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL1992613 | 0.94 | CA12 (0.38) | CA1CA2CA12CA4CA6 | |
| Potassium Ion SCHEMBL10827574 | 0.93 | L3MBTL1 (0.41) | CA1CA2CA12CA4CA6 | |
| Lithium Ion SCHEMBL13278129 | 0.90 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL29373550 | 0.90 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL13277811 | 0.90 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL2000639 | 0.90 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL13277971 | 0.90 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL13277222 | 0.90 | L3MBTL1 (0.42) | CA1CA2CA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338924-A1 | POLYMER, POLYMER ELECTROLYTE AND USE OF SAME | Sumitomo Chemical Company, Limited (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-20110151355-A1 | POLYMER, POLYMER ELECTROLYTE AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |