SCHEMBL2000639

SCHEMBL2000639

O=S(=O)([O-])c1cc(Cl)c(Cl)cc1Cl.[Na+]

nearest known ligand 0.42

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 3/20 0.39
CA1 known ✓ P00915 3/20 0.39
CA2 known ✓ P00918 3/20 0.39
CA4 known ✓ P22748 3/20 0.39
PTGS1 known ✓ P23219 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.42
CA3 P07451 3/20 0.39
CA6 P23280 3/20 0.39
CA5A P35218 3/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA5B Q9Y2D0 3/20 0.39
CA13 Q8N1Q1 2/20 0.39
GUSB P08236 1/20 0.37
CISD1 Q9NZ45 1/20 0.35
PGR P06401 1/20 0.35
CNR1 P21554 1/20 0.35
DUSP5 Q16690 1/20 0.34
CDK1 P06493 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373550 1.00 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
Potassium Ion SCHEMBL10827574 0.98 L3MBTL1 (0.41) L3MBTL1CA12CA1CA2CA3
Potassium Ion SCHEMBL1997078 0.95 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
SCHEMBL13277811 0.95 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
Lithium Ion SCHEMBL13278129 0.95 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
Potassium Ion SCHEMBL29653632 0.95 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
SCHEMBL13277971 0.95 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
SCHEMBL13277222 0.95 L3MBTL1 (0.42) L3MBTL1CA12CA1CA2CA3
SCHEMBL1992613 0.95 CA12 (0.38) L3MBTL1CA12CA1CA2CA3
Potassium Ion SCHEMBL1989757 0.90 CA1 (0.38) L3MBTL1CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027633-A Halogen-free flame-retardant PC/ABS composite material with high impact strength and high thermal deformation temperature 苏州汉扬精密电子有限公司 2024-05-14 CN claimed
CN-117801494-A Wave-absorbing material for automobile radar and preparation method thereof 南京华格电汽塑业有限公司 2024-04-02 CN claimed
CN-117565358-A Preparation method of PC alloy with low water absorption 万华化学集团股份有限公司 2024-02-20 CN claimed
CN-117364280-A Production method of flame-retardant polyester textured yarn 安徽瑞翔纺织科技有限公司 2024-01-09 CN claimed
CN-116948080-A High-temperature flexural modulus modifier and synthetic method and application thereof 宁波公牛电器有限公司 2023-10-27 CN claimed
CN-114023217-B Prism type reflective film for laser printing and manufacturing method thereof 浙江道明光电科技有限公司 2023-09-22 CN claimed
CN-116690882-A Preparation method of polycarbonate foam material 中国科学院长春应用化学研究所 2023-09-05 CN claimed
CN-116554550-A Flame retardant material, polycarbonate composite material and preparation method 公牛集团股份有限公司 2023-08-08 CN claimed
CN-116285280-A Halogen-free flame-retardant super-tough PC composite material and product thereof 汉达精密电子(昆山)有限公司 2023-06-23 CN claimed
CN-116262852-A High-temperature-resistant flame-retardant PC/PAR composite material and product thereof 汉达精密电子(昆山)有限公司 2023-06-16 CN claimed
WO-1994010245-A1 FIRE RETARDING THERMOFORMABLE BLENDS OF COPOLYMER RESINS GENERAL ELECTRIC COMPANY (US) 1994-05-11 WO claimed
US-4776981-A PHTHALIMIDE COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1988-10-11 US claimed
US-4464497-A COPOLYESTER CARBONATE, METAL SALT OF ORGANIC SULFONIC ACID GENERAL ELECTRIC COMPANY (US) 1984-08-07 US claimed
US-4454275-A Flame retardant copolyester-carbonate compositions GENERAL ELECTRIC COMPANY (US) 1984-06-12 US claimed
EP-0103123-A1 Flame retardant copolyester-carbonate compositions GENERAL ELECTRIC COMPANY (US) 1984-03-21 EP claimed
US-4391935-A Flame retardant polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1983-07-05 US claimed
WO-1982002895-A1 FLAME RETARDANT POLYESTER-CARBONATE COMPOSITIONS GEN ELECTRIC (US) 1982-09-02 WO claimed
US-4263201-A ORGANIC ACID METAL SALT, HALOGEN COMPOUND GENERAL ELECTRIC COMPANY (US) 1981-04-21 US claimed
US-4197232-A Flame retardant polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1980-04-08 US claimed
US-3971756-A SILOXANE, ORGANIC ALKALI OR ALKALINE EARTH SALTS GENERAL ELECTRIC COMPANY (US) 1976-07-27 US claimed