Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267 | 0.72 | CES1 (0.38) | — | |
| SCHEMBL2865639 | 0.61 | KMT2A (0.42) | — | |
| SCHEMBL3910501 | 0.61 | GAA (0.50) | TDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL7135216 | 0.60 | TLR9 (0.44) | HSP90AA1 | |
| SCHEMBL1232851 | 0.59 | L3MBTL1 (0.37) | — | |
| SCHEMBL7078045 | 0.59 | PDE6D (0.52) | — | |
| SCHEMBL29732538 | 0.57 | POLB (0.43) | — | |
| SCHEMBL2152999 | 0.57 | MGLL (0.32) | — | |
| SCHEMBL25327968 | 0.57 | TDP2 (0.47) | TDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL3070295 | 0.55 | HPGD (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075383-A1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |