SCHEMBL19909173

SCHEMBL19909173

Cc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C)cc4)ccc2n3-c2cc(C#N)cc(-n3c4ccc(-c5ccc(C)cc5)cc4c4cc(-c5ccc(C)cc5)ccc43)c2-c2cc(C)nc(C)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 1/20 0.37
HSD11B1 P28845 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP2A6 P11509 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
AR P10275 1/20 0.33
CHEK1 O14757 1/20 0.32
PGR P06401 1/20 0.32
AURKA O14965 1/20 0.32
KDR P35968 1/20 0.32
AURKB Q96GD4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913282 0.94 PTGER4 (0.39) MAPKAPK2HSD11B1PIK3CDPIK3CAIRAK4
SCHEMBL22563366 0.90 MAPKAPK2 (0.38) MAPKAPK2HSD11B1PIK3CDPIK3CAIRAK4
SCHEMBL19913283 0.90 CHEK1 (0.37) MAPKAPK2HSD11B1PIK3CDPIK3CAIRAK4
SCHEMBL21414138 0.90 MAPKAPK2 (0.38) MAPKAPK2PIK3CDPIK3CAALDH1A1CYP2A6
SCHEMBL19909501 0.89 CYP1A2 (0.40) ALDH1A1PGR
SCHEMBL25658982 0.88 ALDH1A1 (0.43) MAPKAPK2PIK3CDPIK3CAALDH1A1CYP2A6
SCHEMBL21278805 0.87 MAPKAPK2 (0.34) MAPKAPK2HSD11B1PIK3CDPIK3CAIRAK4
SCHEMBL19909067 0.86 MAPKAPK2 (0.39) MAPKAPK2PIK3CDPIK3CAALDH1A1CYP2A6
SCHEMBL22170356 0.86 PTGER4 (0.36) MAPKAPK2ALDH1A1
SCHEMBL21109678 0.85 MAPKAPK2 (0.38) MAPKAPK2PIK3CDPIK3CAALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPKAPK2 3739/4885HSD11B1 2137/4885PIK3CD 4090/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPKAPK2 3450/4885HSD11B1 1910/4885PIK3CD 4378/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPKAPK2 3739/4885HSD11B1 2137/4885PIK3CD 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.