SCHEMBL19909294

SCHEMBL19909294

N#Cc1cc(C#N)cc(-c2ccc3c4ccccc4n(-c4cc(-c5ccncc5)c(-n5c6ccccc6c6ccc(-c7cc(C#N)cc(C#N)c7)cc65)cc4C#N)c3c2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.34
SQOR Q9Y6N5 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.33
PRKACA P17612 1/20 0.33
CDK8 P49336 1/20 0.33
CLK2 P49760 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CDK9 P50750 1/20 0.33
CDK5 Q00535 1/20 0.33
PRKCQ Q04759 1/20 0.33
ROCK1 Q13464 1/20 0.33
DYRK1A Q13627 1/20 0.33
LRRK2 Q5S007 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
MAPK14 Q16539 2/20 0.33
HPGD P15428 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909165 0.96 FLT3 (0.36) FLT3SQORGSK3BMAPK14HPGD
SCHEMBL19909157 0.94 SQOR (0.34) FLT3SQORNCOA3PRKACACDK8
SCHEMBL19909519 0.94 FLT3 (0.34) FLT3SQORNCOA3PRKACACDK8
SCHEMBL20923860 0.93 SQOR (0.36) FLT3SQORPRKACACDK8CLK2
SCHEMBL19919616 0.93 CYP1A2 (0.40) FLT3SQORGSK3AGSK3BROCK1
SCHEMBL19919781 0.93 FLT3 (0.39) FLT3SQORNCOA3PRKACACDK8
SCHEMBL21414147 0.91 PGR (0.35) PGRCYP11B1CYP11B2IMPDH2
SCHEMBL19909482 0.90 IMPDH2 (0.41) SQORNCOA3PRKACACDK8CLK2
SCHEMBL20923266 0.89 PIK3CA (0.37) SQORPRKACACDK8CLK2GSK3A
SCHEMBL20923862 0.89 IMPDH2 (0.36) FLT3SQORPRKACACDK8CLK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 FLT3 2571/4885SQOR 1580/4885NCOA3 1730/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 FLT3 3269/4885SQOR 225/4885NCOA3 2493/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 FLT3 2571/4885SQOR 1580/4885NCOA3 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.