SCHEMBL19909419

SCHEMBL19909419

N#Cc1c(-n2c3ccc(C(F)(F)F)cc3c3cc(C(F)(F)F)ccc32)cc(-c2ccncc2)cc1-n1c2ccc(C(F)(F)F)cc2c2cc(C(F)(F)F)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.44
DHODH Q02127 2/20 0.36
EPHX2 P34913 1/20 0.36
CHUK O15111 1/20 0.34
ABL1 P00519 1/20 0.34
BCR P11274 1/20 0.34
MAPK14 Q16539 1/20 0.34
HRH1 P35367 1/20 0.33
HTR6 P50406 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
RXFP1 Q9HBX9 1/20 0.32
DGAT1 O75907 1/20 0.32
SOAT1 P35610 1/20 0.32
KCNH2 Q12809 1/20 0.32
CYP19A1 P11511 1/20 0.32
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
MAPT P10636 2/20 0.32
ABCG2 Q9UNQ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909343 0.94 KIF11 (0.39) KIF11DHODHEPHX2MAPK14HRH1
SCHEMBL19913179 0.93 KIF11 (0.38) KIF11DHODHEPHX2HRH1HTR6
SCHEMBL19909344 0.90 KIF11 (0.44) KIF11DHODHEPHX2NPC1RAB9A
SCHEMBL19909449 0.89 KIF11 (0.41) KIF11EPHX2MAPK14
SCHEMBL19909304 0.89 KIF11 (0.44) KIF11DHODHMAPK14NPC1RAB9A
SCHEMBL19913180 0.89 KIF11 (0.36) KIF11DHODHMAPK14HRH1HTR6
SCHEMBL19909372 0.88 KIF11 (0.39) KIF11DHODHEPHX2MAPK14NPC1
SCHEMBL19909345 0.87 KIF11 (0.43) KIF11EPHX2CYP19A1MAPTABCG2
SCHEMBL19903568 0.87 RXRA (0.35) KIF11DHODHKCNH2MAPTALDH1A1
SCHEMBL20620027 0.86 HTR2B (0.43) KIF11EPHX2HTR6NPC1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 KIF11 3067/4885DHODH 2141/4885EPHX2 969/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 KIF11 3082/4885DHODH 1080/4885EPHX2 745/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 KIF11 3067/4885DHODH 2141/4885EPHX2 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.