SCHEMBL19909486

SCHEMBL19909486

Cc1nc(C)nc(-c2ccc3c4ccccc4n(-c4cc(-c5ccncc5)cc(-n5c6ccccc6c6ccc(-c7nc(C)nc(C)n7)cc65)c4C#N)c3c2)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 2/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
CYP11B2 P19099 1/20 0.34
PIK3R2 O00459 4/20 0.34
POLB P06746 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
ADORA1 P30542 2/20 0.33
MAPK14 Q16539 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
ADORA2A P29274 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
USP2 O75604 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.32
PIK3CA P42336 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909023 0.95 PIK3CA (0.34) SQORMEN1KMT2APOLBRXFP1
SCHEMBL19913198 0.94 SQOR (0.35) SQORMEN1KMT2ACYP11B2PIK3R2
SCHEMBL19943081 0.91 PDE9A (0.34) MEN1KMT2ACYP11B2POLBMAPT
SCHEMBL19909215 0.89 ALDH1A1 (0.33) MEN1KMT2ACYP11B2POLBMAPT
SCHEMBL19909021 0.89 MEN1 (0.43) SQORMEN1KMT2ACYP11B2PIK3R2
SCHEMBL23912070 0.89 CYP11B2 (0.46) SQORMEN1KMT2ACYP11B2RXFP1
SCHEMBL21414246 0.88 CYP1A2 (0.35) MEN1KMT2AMAPTUSP2CYP1A2
SCHEMBL24656014 0.88 L3MBTL1 (0.36) SQORMEN1KMT2ACYP11B2ADORA1
SCHEMBL19913197 0.88 KDM4E (0.33) SQORMEN1KMT2APOLBRXFP1
SCHEMBL22170355 0.88 PTGER4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 SQOR 225/4885MEN1 2554/4885KMT2A 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.