SCHEMBL19909522

SCHEMBL19909522

Cc1cc(-c2cc(-n3c4cc(C(F)(F)F)ccc4c4ccc(C(F)(F)F)cc43)c(C#N)cc2-n2c3cc(C(F)(F)F)ccc3c3ccc(C(F)(F)F)cc32)cc(C)n1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.39
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MAT2A P31153 5/20 0.35
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35
PSENEN Q9NZ42 1/20 0.35
XDH P47989 1/20 0.34
GRM5 P41594 2/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33
CYP11B2 P19099 1/20 0.33
GRM2 Q14416 1/20 0.33
CTSS P25774 2/20 0.33
CTSK P43235 2/20 0.33
PDE10A Q9Y233 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909515 0.96 KIF11 (0.43) KIF11TSHRSMN1; SMN2MAT2APSEN1
SCHEMBL19913225 0.96 KIF11 (0.36) KIF11TSHRSMN1; SMN2MAT2APSEN1
SCHEMBL19913228 0.92 KIF11 (0.40) KIF11TSHRSMN1; SMN2MAT2APSEN1
SCHEMBL19919792 0.92 TSHR (0.38) KIF11TSHRSMN1; SMN2MAT2APSEN1
SCHEMBL19919651 0.90 ALOX5AP (0.35) KIF11TSHRSMN1; SMN2PSEN1PSEN2
SCHEMBL19913218 0.90 CSNK1D (0.33) KIF11SMN1; SMN2CTSSCTSK
SCHEMBL19909076 0.89 KIF11 (0.43) KIF11TSHRSMN1; SMN2MAT2APSEN1
SCHEMBL19919645 0.89 METAP2 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL22563711 0.89 KIF11 (0.39) KIF11TSHRSMN1; SMN2MAT2APSEN1
SCHEMBL19913256 0.88 ALOX5AP (0.34) KIF11TSHRSMN1; SMN2PSEN1PSEN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 KIF11 3067/4885TSHR 3463/4885SMN1; SMN2 4471/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 KIF11 3082/4885TSHR 3186/4885SMN1; SMN2 4607/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 KIF11 3067/4885TSHR 3463/4885SMN1; SMN2 4471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.