Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.31 |
| ▸ | KIT | P10721 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924427 | 0.92 | HTT (0.33) | SMN1; SMN2ALDH1A1L3MBTL1PDGFRAKIT | |
| SCHEMBL17904775 | 0.92 | NR3C1 (0.34) | NR3C1SMN1; SMN2ALDH1A1L3MBTL1PDGFRA | |
| SCHEMBL17905666 | 0.89 | XBP1 (0.34) | NR3C1SMN1; SMN2PDGFRANPC1RAB9A | |
| SCHEMBL25022987 | 0.86 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1PDGFRAKITHPGD | |
| SCHEMBL21339079 | 0.86 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1PDGFRAKITHPGD | |
| SCHEMBL17905151 | 0.85 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1PDGFRAKITNPC1 | |
| SCHEMBL17905093 | 0.85 | RAB9A (0.35) | SMN1; SMN2NPC1RAB9AHPGDLMNA | |
| SCHEMBL17904858 | 0.84 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL17905086 | 0.84 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL17905149 | 0.83 | XBP1 (0.35) | NR3C1SMN1; SMN2ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231452-B2 | Thiopicolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-03-19 | — | — | US | disclosed |
| US-20180055052-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180055052-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180055052-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | TST, TPMT, CYP51A1 | NR3C1 4103/4885SMN1; SMN2 3840/4885ALDH1A1 1190/4885 |
| US-10231452-B2 | Thiopicolinamide compounds with fungicidal activity | TST, TPMT, CYP51A1 | NR3C1 4103/4885SMN1; SMN2 3840/4885ALDH1A1 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.