Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534033 | 0.70 | PKM (0.33) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL1148182 | 0.69 | MMP2 (0.41) | OPRM1MMP2MMP9ALDH1A1OPRK1 | |
| SCHEMBL1260071 | 0.67 | OPRM1 (0.37) | OPRM1KCNH2MMP2MMP9ALDH1A1 | |
| SCHEMBL15524924 | 0.64 | OPRM1 (0.38) | OPRM1KCNH2MMP2MMP9ALDH1A1 | |
| SCHEMBL18086910 | 0.62 | OPRM1 (0.37) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL19915046 | 0.62 | ALDH1A1 (0.38) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL11432661 | 0.62 | ALDH1A1 (0.41) | OPRM1MMP2MMP9ALDH1A1POLB | |
| SCHEMBL28487408 | 0.62 | OPRM1 (0.33) | OPRM1KCNH2MMP2MMP9ALDH1A1 | |
| SCHEMBL21524 | 0.62 | OPRM1 (0.45) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL20954171 | 0.62 | OPRM1 (0.36) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155530-B2 | Urea-oxaziridines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210155600-A1 | Urea-Oxaziridines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-27 | — | — | US | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155530-B2 | Urea-oxaziridines | TST, METTL14, TMT1A | OPRM1 141/4885GRIN2D 1835/4885GRIN3B 2634/4885 |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | AHR, TYR, CYP1A1 | OPRM1 544/4885GRIN2D 3561/4885GRIN3B 3714/4885 |
| US-20210155600-A1 | Urea-Oxaziridines | TST, METTL14, TMT1A | OPRM1 141/4885GRIN2D 1835/4885GRIN3B 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.