Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 11/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917755 | 0.90 | TRPA1 (0.47) | TRPA1KMT2ATRPV1 | |
| SCHEMBL19917774 | 0.90 | TRPA1 (0.46) | TRPA1KIF11PPARD | |
| SCHEMBL19917762 | 0.87 | NPC1 (0.46) | KMT2A | |
| SCHEMBL19917704 | 0.85 | TRPA1 (0.50) | TRPA1KMT2A | |
| SCHEMBL19917764 | 0.85 | CASR (0.39) | TRPA1KMT2A | |
| SCHEMBL19917771 | 0.83 | KMT2A (0.37) | TRPA1KMT2A | |
| SCHEMBL16894260 | 0.82 | KMT2A (0.57) | TRPA1KMT2A | |
| SCHEMBL19917760 | 0.81 | TRPA1 (0.46) | TRPA1KMT2AKIF11PPARDPOLQ | |
| SCHEMBL19917753 | 0.81 | TRPA1 (0.41) | TRPA1KMT2A | |
| SCHEMBL16894100 | 0.79 | TRPA1 (0.54) | TRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900642-B1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-02-28 | — | — | EP | disclosed |