Sugi Predict

Sugi Predict / Compounds / SCHEMBL19919728

SCHEMBL19919728

SCHEMBL19919728

Cc1cc(C)cc(-c2ccc3c4ccccc4n(-c4cc(C#N)c(-c5ccncc5)cc4-n4c5ccccc5c5ccc(-c6cc(C)cc(C)c6)cc54)c3c2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 1/20 0.36
▸ SQOR Q9Y6N5 2/20 0.35
▸ XDH P47989 1/20 0.35
▸ LMNA P02545 3/20 0.35
▸ CYP2C19 P33261 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ PDE5A O76074 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ PDE4A P27815 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ PDE4B Q07343 1/20 0.35
▸ PDE4C Q08493 1/20 0.35
▸ PDE4D Q08499 1/20 0.35
▸ PDE3B Q13370 1/20 0.35
▸ PDE3A Q14432 1/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919631 0.95 PDE3B (0.38) XDHLMNACYP2C19KDM4EPDE5A
SCHEMBL19913126 0.94 MAPK14 (0.36) MAPK14SQORXDHLMNACYP2C19
SCHEMBL19919626 0.94 MAPK14 (0.36) MAPK14SQORXDHLMNACYP2C19
SCHEMBL19919549 0.93 MAPK14 (0.39) MAPK14SQORXDHLMNACYP2C19
SCHEMBL19919758 0.93 ALDH1A1 (0.38) MAPK14SQORXDHLMNACYP2C19
SCHEMBL19919628 0.90 SQOR (0.34) MAPK14SQORXDHLMNACYP2C19
SCHEMBL19909263 0.89 ALDH1A1 (0.40) SQORXDHLMNACYP2C19KDM4E
SCHEMBL19913201 0.89 IMPDH2 (0.41) SQORXDHCYP2C19NPSR1CYP1A2
SCHEMBL19909014 0.89 PDE3B (0.38) SQORXDHLMNACYP2C19KDM4E
SCHEMBL19909519 0.88 FLT3 (0.34) MAPK14SQORXDHHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 MAPK14 2544/4885SQOR 1580/4885XDH 483/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 MAPK14 2787/4885SQOR 225/4885XDH 40/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 MAPK14 2544/4885SQOR 1580/4885XDH 483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.