SCHEMBL1992172

SCHEMBL1992172

O=COc1cccc(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.43
SLC6A4 P31645 3/20 0.43
SLC6A3 Q01959 2/20 0.43
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
BCHE P06276 1/20 0.39
CTSL P07711 1/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
ERN1 O75460 1/20 0.36
TRPA1 O75762 1/20 0.34
NFE2L2 Q16236 1/20 0.33
HTR1A P08908 2/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28366367 0.98 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL95849 0.82 NFE2L2 (0.39) CTSLCTSSCTSKNFE2L2HPGD
SCHEMBL18468359 0.81 CTSS (0.45) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL1993754 0.80 CTSL (0.39) CES2CES1CTSLCTSSCTSK
SCHEMBL27559493 0.80 NFE2L2 (0.38) CTSLCTSSCTSKNFE2L2HPGD
SCHEMBL29068856 0.79 MRGPRX4 (0.41) SLC6A2HTR1AKMT2AHPGD
SCHEMBL10209572 0.79 ALDH1A1 (0.30)
SCHEMBL9657539 0.79 ERN1 (0.34) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL20414022 0.79 LMNA (0.38) ERN1KMT2AHPGD
SCHEMBL27295958 0.79 LMNA (0.36) SLC6A2SLC6A4SLC6A3ERN1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed