SCHEMBL28366367

SCHEMBL28366367

O=COc1cccc(F)c1F.[KH]

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
SLC6A3 Q01959 2/20 0.42
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
BCHE P06276 1/20 0.38
CTSL P07711 1/20 0.37
CTSS P25774 1/20 0.37
CTSK P43235 1/20 0.37
ERN1 O75460 1/20 0.35
TRPA1 O75762 1/20 0.33
NFE2L2 Q16236 1/20 0.32
HTR1A P08908 2/20 0.31
KMT2A Q03164 1/20 0.31
GRM2 Q14416 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1992172 0.98 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL95849 0.80 NFE2L2 (0.39) CTSLCTSSCTSKNFE2L2HPGD
SCHEMBL18468359 0.80 CTSS (0.45) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL1993754 0.78 CTSL (0.39) CES2CES1CTSLCTSSCTSK
SCHEMBL27559493 0.78 NFE2L2 (0.38) CTSLCTSSCTSKNFE2L2HPGD
SCHEMBL27295958 0.78 LMNA (0.36) SLC6A2SLC6A4SLC6A3ERN1NFE2L2
SCHEMBL9657539 0.78 ERN1 (0.34) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL28121126 0.78 ERN1 (0.34) SLC6A2SLC6A4SLC6A3CES2CES1
SCHEMBL29068856 0.78 MRGPRX4 (0.41) SLC6A2HTR1AKMT2AHPGD
SCHEMBL10209572 0.78 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110540610-B (methyl) acrylate polymer and preparation method thereof 浙江省化工研究院有限公司 2021-08-20 CN disclosed
CN-110540610-A (methyl) acrylate polymer and preparation method thereof ZHEJIANG RES INST CHEMICAL IND LTD 2019-12-06 CN disclosed