Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238812 | 0.85 | GAA (0.58) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL9570228 | 0.83 | ALDH1A1 (0.96) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL8134520 | 0.81 | ALDH1A1 (0.73) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL27645331 | 0.81 | GAA (0.45) | ALDH1A1GAAMAPTKDM4ETP53 | |
| SCHEMBL5866593 | 0.80 | ALDH1A1 (0.71) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL10187288 | 0.79 | ALDH1A1 (0.80) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL17366264 | 0.79 | ALDH1A1 (0.69) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL7265202 | 0.79 | ALDH1A1 (0.80) | ALDH1A1GAATLR8MAPTKDM4E | |
| SCHEMBL278545 | 0.79 | KDM1A (0.54) | ALDH1A1GAAMAPTRXRAKDM1A | |
| SCHEMBL2973838 | 0.77 | GAA (0.52) | ALDH1A1GAAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322688-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-10-12 | — | — | US | disclosed |
| US-10787421-B2 | Substituted anilines for treatment of animal diseases | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-10787421-B2 | Substituted anilines for treatment of animal diseases | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190218190-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-07-18 | — | — | US | disclosed |
| US-20190218190-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-07-18 | — | — | US | disclosed |
| US-10221143-B2 | Substituted anilines for treatment of animal diseases | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-10221143-B2 | Substituted anilines for treatment of animal diseases | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| US-20180065936-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180065936-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180065936-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322688-A1 | THERAPEUTIC COMPOUNDS | IL5, IL15, IL4 | ALDH1A1 495/4885GAA 2087/4885TLR8 1831/4885 |
| US-10787421-B2 | Substituted anilines for treatment of animal diseases | IL5, IL4, IL15 | ALDH1A1 424/4885GAA 1979/4885TLR8 1433/4885 |
| US-20190218190-A1 | THERAPEUTIC COMPOUNDS | IL5, IL4, IL15 | ALDH1A1 692/4885GAA 2104/4885TLR8 1551/4885 |
| US-20180065936-A1 | THERAPEUTIC COMPOUNDS | IL5, IL4, IL15 | ALDH1A1 692/4885GAA 2104/4885TLR8 1551/4885 |
| US-10221143-B2 | Substituted anilines for treatment of animal diseases | IL5, IL4, IL15 | ALDH1A1 513/4885GAA 1942/4885TLR8 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.