Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238812 | 0.84 | GAA (0.58) | GAAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL24133302 | 0.81 | LMNA (0.40) | MAPTKDM4EALDH1A1POLBUSP2 | |
| SCHEMBL19923313 | 0.81 | ALDH1A1 (0.69) | GAAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL2973838 | 0.80 | GAA (0.52) | GAAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL1599760 | 0.80 | ALDH1A1 (0.56) | GAAMAPTKDM4EALDH1A1POLB | |
| SCHEMBL19617651 | 0.79 | GABRA1 (0.37) | GAAMAPTALDH1A1POLBHTT | |
| SCHEMBL282475 | 0.79 | ALDH1A1 (0.47) | MAPTKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL29970124 | 0.79 | GABRA1 (0.37) | GAAMAPTALDH1A1POLBHTT | |
| SCHEMBL17034855 | 0.79 | GAA (0.40) | GAAMAPTALDH1A1HTTTSHR | |
| SCHEMBL3162042 | 0.77 | THRB (0.45) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180097-A | Novel phosphinic acid-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |