SCHEMBL19923482

SCHEMBL19923482

O=C1CN(Cc2ccccc2)C(=O)N1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 3/20 0.48
HDAC6 Q9UBN7 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 5/20 0.42
POLB P06746 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 4/20 0.42
F2 P00734 1/20 0.42
PLG P00747 1/20 0.42
ELANE P08246 1/20 0.42
CTSG P08311 1/20 0.42
CMA1 P23946 1/20 0.42
CTRC Q99895 1/20 0.42
DRD3 P35462 1/20 0.41
KCNH2 Q12809 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
EPHX2 P34913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923712 0.83 ACHE (0.35) ENPP2KMT2AMEN1
SCHEMBL19923534 0.83 ENPP2 (0.49) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL19923667 0.80 ENPP2 (0.47) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL19923494 0.79 ENPP2 (0.46) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL1488276 0.75 L3MBTL1 (0.56) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL4955033 0.75 HDAC6 (0.69) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL19923485 0.75 MEN1 (0.32) KMT2AMEN1CTSGCMA1
SCHEMBL6938737 0.73 ENPP2 (0.53) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL7212064 0.73 ENPP2 (0.53) ENPP2HDAC6L3MBTL1KMT2APOLB
SCHEMBL7212061 0.73 ENPP2 (0.53) ENPP2HDAC6L3MBTL1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ENPP2 3997/4885HDAC6 117/4885L3MBTL1 3588/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ENPP2 3888/4885HDAC6 151/4885L3MBTL1 3763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.