SCHEMBL19923712

SCHEMBL19923712

CCN1CC(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C1=O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SHMT2 P34897 1/20 0.33
ENPP2 Q13822 1/20 0.33
IDH1 O75874 1/20 0.32
MAPK1 P28482 1/20 0.31
PLA2G7 Q13093 1/20 0.31
LMNA P02545 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923482 0.83 ENPP2 (0.48) MEN1KMT2AENPP2
SCHEMBL19923593 0.78 PLA2G7 (0.43) MEN1KMT2APLA2G7
SCHEMBL19923485 0.76 MEN1 (0.32) MEN1KMT2A
SCHEMBL19923512 0.75 NPC1 (0.47) MEN1KMT2A
SCHEMBL19923473 0.74 GRM4 (0.45) KMT2AIDH1MAPK1
SCHEMBL19923761 0.73 F2 (0.32)
SCHEMBL19923560 0.72 F2 (0.31)
SCHEMBL6031788 0.71 ENPP2 (0.60) MEN1KMT2AENPP2
SCHEMBL19923571 0.70 F2 (0.30)
SCHEMBL19923667 0.69 ENPP2 (0.47) MEN1KMT2AENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ACHE 1904/4885MEN1 2213/4885KMT2A 1080/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ACHE 1932/4885MEN1 2164/4885KMT2A 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.