SCHEMBL19923629

SCHEMBL19923629

CCC1C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1CC

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
USP2 O75604 1/20 0.34
GRM5 P41594 1/20 0.33
CES2 O00748 1/20 0.33
ADORA3 P0DMS8 2/20 0.33
LMNA P02545 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
AADAT Q8N5Z0 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30
ADORA1 P30542 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923469 0.87 EHMT2 (0.46) EHMT2NPSR1MAPK1
SCHEMBL19923702 0.84 CES2 (0.34) SMN1; SMN2CES2ADORA3LMNAEHMT2
SCHEMBL19923602 0.83 SMO (0.37) SMN1; SMN2ADORA3LMNAEHMT2ATM
SCHEMBL19923495 0.83 CES2 (0.33) CES2ADORA3LMNAEHMT2NPSR1
SCHEMBL19923630 0.81 LMNA (0.38) SMN1; SMN2ADORA3LMNAATMNPSR1
SCHEMBL19923608 0.81 CYP1A2 (0.38) SMN1; SMN2CES2LMNANPSR1
SCHEMBL19923655 0.81 PLK1 (0.38) GRM5CES2
SCHEMBL19923619 0.75 PLK1 (0.40) CES2LMNANPSR1OPRM1OPRL1
SCHEMBL19923513 0.75 L3MBTL1 (0.34)
SCHEMBL22549005 0.73 SMN1; SMN2 (0.47) SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN SMN1; SMN2 1697/4885USP2 962/4885GRM5 2422/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM SMN1; SMN2 1924/4885USP2 975/4885GRM5 2337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.