SCHEMBL19923602

SCHEMBL19923602

CCN1C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)C1C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMO Q99835 3/20 0.37
ATM Q13315 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CNR2 P34972 1/20 0.34
LMNA P02545 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923769 0.85 SMO (0.53) SMOEHMT2MEN1KMT2A
SCHEMBL19923629 0.83 SMN1; SMN2 (0.34) ATMSMN1; SMN2NPSR1LMNAADORA3
SCHEMBL19923630 0.82 LMNA (0.38) ATMSMN1; SMN2NPSR1LMNAADORA3
SCHEMBL19923746 0.79 GRM4 (0.35) SMO
SCHEMBL19923424 0.79 TSHR (0.34) SMOATMMEN1KMT2A
SCHEMBL19923679 0.78 LOX (0.39) SMOSMN1; SMN2NPSR1LMNAMEN1
SCHEMBL19923550 0.76 GRM4 (0.47) KMT2A
SCHEMBL19923670 0.74 L3MBTL1 (0.35) CNR2
SCHEMBL19923469 0.74 EHMT2 (0.46) SMONPSR1EHMT2MEN1KMT2A
SCHEMBL19923702 0.73 CES2 (0.34) SMN1; SMN2LMNAADORA3EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN SMO 4561/4885ATM 2253/4885SMN1; SMN2 1697/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM SMO 4608/4885ATM 2378/4885SMN1; SMN2 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.