SCHEMBL5439673

SCHEMBL5439673

O=C1N(CCl)C(=O)C(c2ccccc2)(c2ccccc2)N1Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.46
CTSG P08311 2/20 0.46
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
CMA1 P23946 1/20 0.46
CTRC Q99895 1/20 0.46
NPSR1 Q6W5P4 2/20 0.43
CYP2C19 P33261 3/20 0.41
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40
MGLL Q99685 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
PRTN3 P24158 1/20 0.39
CNR1 P21554 1/20 0.38
EP300 Q09472 1/20 0.37
HTR1A P08908 1/20 0.37
HTR7 P34969 1/20 0.37
HTR6 P50406 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923635 0.90 ELANE (0.53) ELANECTSGF2PLGCMA1
SCHEMBL14372430 0.86 NPSR1 (0.49) ELANECTSGF2PLGCMA1
SCHEMBL5432681 0.86 ELANE (0.44) ELANECTSGF2PLGCMA1
SCHEMBL5438240 0.76 ELANE (0.45) ELANECTSGF2PLGCMA1
SCHEMBL19923487 0.76 ELANE (0.41) ELANECTSGF2PLGCMA1
SCHEMBL19923500 0.75 ELANE (0.39) ELANECTSGF2PLGCMA1
SCHEMBL19923625 0.74 NPSR1 (0.42) ELANECTSGF2PLGCMA1
SCHEMBL15461432 0.74 OPRM1 (0.46) ELANECTSGF2PLGCMA1
SCHEMBL11424602 0.73 HTR1A (0.40) HTR1AHTR7HTR6
SCHEMBL19923618 0.73 NPSR1 (0.41) ELANECTSGF2PLGCMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249563-A1 PROCESS FOR PREPARING FOSPHENYTOIN DR. REDDY'S LABORATORIES, INC. 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249563-A1 PROCESS FOR PREPARING FOSPHENYTOIN FOS, FIP1L1, FOSB ELANE 3308/4885CTSG 600/4885F2 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.