SCHEMBL5438240

SCHEMBL5438240

O=C1N(COP(=O)(OCc2ccccc2)OCc2ccccc2)C(=O)C(c2ccccc2)(c2ccccc2)N1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.45
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.36
CTSG P08311 2/20 0.36
F2 P00734 1/20 0.36
PLG P00747 1/20 0.36
CMA1 P23946 1/20 0.36
CTRC Q99895 1/20 0.36
TP53 P04637 2/20 0.35
MDM2 Q00987 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
PRTN3 P24158 1/20 0.34
CYP2C19 P33261 3/20 0.34
ADRA2A P08913 1/20 0.33
NISCH Q9Y2I1 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923635 0.79 ELANE (0.53) ELANECTSGF2PLGCMA1
SCHEMBL5439673 0.76 ELANE (0.46) ELANECTSGF2PLGCMA1
SCHEMBL5438242 0.76 ACP3 (0.33) TSHRTP53MDM2
SCHEMBL14372430 0.75 NPSR1 (0.49) ELANECTSGF2PLGCMA1
SCHEMBL5432681 0.75 ELANE (0.44) ELANECTSGF2PLGCMA1
SCHEMBL5335343 0.74 CNR1 (0.49) ELANE
SCHEMBL12769594 0.73 ELANE (0.53) ELANELMNATSHRALDH1A1
SCHEMBL15461432 0.69 OPRM1 (0.46) ELANECTSGF2PLGCMA1
SCHEMBL5436021 0.69 ALDH1A1 (0.39) NPSR1ALDH1A1
SCHEMBL206609 0.69 TSHR (0.68) ELANETSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249563-A1 PROCESS FOR PREPARING FOSPHENYTOIN DR. REDDY'S LABORATORIES, INC. 2007-10-25 US disclosed
US-20070249563-A1 PROCESS FOR PREPARING FOSPHENYTOIN DR. REDDY'S LABORATORIES, INC. 2007-10-25 US disclosed
US-20070249563-A1 PROCESS FOR PREPARING FOSPHENYTOIN DR. REDDY'S LABORATORIES, INC. 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249563-A1 PROCESS FOR PREPARING FOSPHENYTOIN FOS, FIP1L1, FOSB ELANE 3308/4885LMNA 3623/4885TSHR 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.