SCHEMBL19923744

SCHEMBL19923744

CC[Si](CC)(CC)N1C(=O)CN(C2CCCCC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TP53 P04637 2/20 0.35
TSHR P16473 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923504 0.89 MEN1 (0.40) CTSGCMA1MEN1KMT2AALDH1A1
SCHEMBL19923627 0.81 CTSG (0.41) CTSGCMA1MEN1KMT2AALDH1A1
SCHEMBL6232185 0.72 CTSG (0.44) CTSGCMA1MEN1KMT2AGSK3A
SCHEMBL19923636 0.71 ALDH1A1 (0.43) CTSGCMA1MEN1KMT2AALDH1A1
SCHEMBL10767118 0.70 POLB (0.47) CTSGCMA1MEN1KMT2AALDH1A1
SCHEMBL19923461 0.70 OPRM1 (0.38) GSK3AGSK3BALDH1A1LMNAPOLB
SCHEMBL6237189 0.70 CTSG (0.45) CTSGCMA1MEN1KMT2AALDH1A1
SCHEMBL19923649 0.70 KMT2A (0.33) KMT2AALDH1A1GAAMAPT
SCHEMBL19923467 0.70 ALDH1A1 (0.31) ALDH1A1GAAMAPT
SCHEMBL19923743 0.69 OPRM1 (0.38) GSK3AGSK3BALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN CTSG 1654/4885CMA1 4120/4885MEN1 2213/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM CTSG 1736/4885CMA1 3987/4885MEN1 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.