Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 7/20 | 0.34 |
| ▸ | PLK2 | Q9NYY3 | 7/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923543 | 0.90 | OPRM1 (0.37) | OPRM1OPRL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923528 | 0.86 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923461 | 0.83 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923619 | 0.78 | PLK1 (0.40) | OPRM1OPRL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923695 | 0.78 | ALDH1A1 (0.46) | OPRM1OPRL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923657 | 0.75 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923668 | 0.73 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19923442 | 0.72 | — | — | |
| SCHEMBL19923682 | 0.70 | L3MBTL1 (0.33) | — | |
| SCHEMBL19923744 | 0.69 | CTSG (0.39) | OPRM1OPRL1ALDH1A1CYP2C19GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | claimed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | claimed |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | disclosed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | PARG, HNMT, PARN | OPRM1 1259/4885OPRL1 2805/4885ALDH1A1 2648/4885 |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | HNMT, PARG, PAM | OPRM1 1515/4885OPRL1 2784/4885ALDH1A1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.