Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924764 | 1.00 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL19924784 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ALOX15TACR1CTSLCTSS | |
| SCHEMBL19924783 | 0.91 | ALDH1A1 (0.53) | ALDH1A1ALOX15TACR1CTSLCTSS | |
| SCHEMBL7452849 | 0.79 | CTSL (0.58) | ITGB3ITGA2BALDH1A1TACR1CTSL | |
| SCHEMBL1795688 | 0.78 | TGM2 (0.60) | ITGB3ITGA2BTACR1CTSLCTSS | |
| SCHEMBL4368353 | 0.78 | FPR2 (0.62) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL3987614 | 0.78 | FPR2 (0.62) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL220648 | 0.78 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL7372270 | 0.78 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 | |
| SCHEMBL479010 | 0.78 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018042343-A2 | COMPOUNDS THAT INHIBIT 3C AND 3CL PROTEASES AND METHODS OF USE THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-08 | — | — | WO | disclosed |