Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638942 | 0.81 | ENPP2 (0.46) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL28919831 | 0.78 | ALDH1A1 (0.43) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL29418123 | 0.74 | ALDH1A1 (0.50) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL165536 | 0.74 | ALDH1A1 (0.50) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL911112 | 0.73 | TSHR (0.43) | CA2TSHRCA1ENPP2ALDH1A1 | |
| SCHEMBL29325811 | 0.72 | ALDH1A1 (0.47) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL29420321 | 0.72 | ALDH1A1 (0.47) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL12424043 | 0.71 | ALDH1A1 (0.44) | TSHRENPP2ALDH1A1ALOX15MAPT | |
| SCHEMBL5953252 | 0.71 | ENPP2 (0.64) | CA2TSHRCA1TP53ENPP2 | |
| SCHEMBL22182310 | 0.70 | ALDH1A1 (0.45) | CA2TSHRCA1TP53ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214507-A1 | BORONIC ACID MONOMERS AND METHODS OF MAKING BORONIC ACID MONOMERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-07-15 | — | — | US | disclosed |
| US-20180065980-A1 | CYANATED BENZOXANTHENE AND BENZOTHIOXANTHENE COMPOUNDS | BASF SE (DE) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065980-A1 | CYANATED BENZOXANTHENE AND BENZOTHIOXANTHENE COMPOUNDS | CBR3, CBR1, NR2E3 | CA2 1100/4885TSHR 1449/4885CA1 1670/4885 |
| US-20210214507-A1 | BORONIC ACID MONOMERS AND METHODS OF MAKING BORONIC ACID MONOMERS | MMAB, ME1, BPGM | CA2 227/4885TSHR 4497/4885CA1 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.