Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951494 | 0.81 | TRPA1 (0.39) | TSHRACHEENPP2ALDH1A1CA1 | |
| SCHEMBL28994175 | 0.80 | TSHR (0.43) | TSHRACHEENPP2ORAI1ORAI2 | |
| SCHEMBL14703738 | 0.78 | ENPP2 (0.46) | TSHRACHEENPP2ORAI1ORAI2 | |
| SCHEMBL22000805 | 0.75 | TSHR (0.38) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL5953252 | 0.73 | ENPP2 (0.64) | TSHRENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL12424043 | 0.73 | ALDH1A1 (0.44) | TSHRENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL19929264 | 0.73 | CA2 (0.44) | TSHRENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL126881 | 0.73 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL7181071 | 0.72 | TSHR (0.45) | TSHRACHEENPP2ORAI1ORAI2 | |
| SCHEMBL13052533 | 0.72 | CYP2A6 (0.39) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115928264-A | Preparation method of metal-containing near-stoichiometric continuous silicon carbide fiber | 湖南泽睿新材料有限公司 | 2023-04-07 | — | — | CN | claimed |
| US-8921299-B2 | Detergents having acceptable color | THE PROCTER & GAMBLE COMPANY (US) | 2014-12-30 | — | — | US | claimed |
| CN-119716054-A | Fluorescent paper chip for detecting staphylococcus aureus and preparation method and application thereof | 南京师范大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119716050-A | Fluorescent paper chip for detecting escherichia coli O157: H7 as well as preparation method and application thereof | 南京师范大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119192137-A | Inhibition of human integrin alpha4β7 | 莫菲克医疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-112682031-B | Oil field interwell tracer, tracing method and fracturing fluid | 中国石油化工股份有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2024126697-A1 | HIGH STRENGTH LIQUID PROTEASE FORMULATIONS | NOVOZYMES A/S (DK) | 2024-06-20 | — | — | WO | disclosed |
| EP-4379029-A1 | POLYPEPTIDES AND COMPOSITIONS COMPRISING SUCH POLYPEPTIDES | Novozymes A/S (DK) | 2024-06-05 | — | — | EP | disclosed |
| EP-3647398-B1 | CLEANING COMPOSITIONS CONTAINING DISPERSINS V | HENKEL AG & CO KGAA (DE) | 2024-05-15 | — | — | EP | disclosed |
| US-20240132808-A1 | Storage-Stable Hydrolase Containing Liquids | BASF SE (DE) | 2024-04-25 | — | — | US | disclosed |
| EP-4305146-A1 | POLYPEPTIDE VARIANTS | Novozymes A/S (DK) | 2024-01-17 | — | — | EP | disclosed |
| EP-1924677-A1 | STABILIZATION OF CONCENTRATED LIQUID ENZYME ADDITIVES | Novozymes A/S (DK) | 2008-05-28 | — | — | EP | disclosed |
| US-20070060493-A1 | Stabilization of concentrated liquid enzyme additives | NOVOZYMES A/S (DK) | 2007-03-15 | — | — | US | disclosed |
| WO-2007025549-A1 | STABILIZATION OF CONCENTRATED LIQUID ENZYME ADDITIVES | NOVOZYMES A/S (DK) | 2007-03-08 | — | — | WO | disclosed |
| EP-1341793-B1 | CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2007-01-17 | — | — | EP | disclosed |
| US-20040266799-A1 | CRF receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES, INC. | 2004-12-30 | — | — | US | disclosed |
| US-6747034-B2 | CORTICOTROPIN-RELEASING FACTOR (CRF); SUCH AS 4-CHLORO-2-METHYL-5-NITRO-8-(2,4-DICHLORO)PHENYL-1,7-NAPHTHYRIDINE FOR TREATING STROKE, ANXIETY, DEPRESSION, AND/OR IRRITABLE BOWEL SYNDROME | NEUROCRINE BIOSCIENCES, INC. | 2004-06-08 | — | — | US | disclosed |
| EP-1341793-A2 | CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | Neurocrine Biosciences, Inc. (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20020151557-A1 | CRF receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES, INC | 2002-10-17 | — | — | US | disclosed |
| WO-2002040480-A2 | CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266799-A1 | CRF receptor antagonists and methods relating thereto | CRHR1, CRH, CRHR2 | TSHR 162/4885ACHE 2077/4885ENPP2 421/4885 |
| US-20020151557-A1 | CRF receptor antagonists and methods relating thereto | CRHR1, CRH, CRHR2 | TSHR 162/4885ACHE 2077/4885ENPP2 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.