Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143184 | 0.88 | — | — | |
| SCHEMBL21155793 | 0.87 | — | — | |
| SCHEMBL16937782 | 0.85 | — | — | |
| SCHEMBL7565117 | 0.80 | — | — | |
| SCHEMBL13453353 | 0.80 | — | — | |
| SCHEMBL172631 | 0.80 | — | — | |
| SCHEMBL25633457 | 0.75 | ALOX5 (0.32) | — | |
| SCHEMBL21897308 | 0.75 | — | — | |
| SCHEMBL22931830 | 0.71 | — | — | |
| SCHEMBL16713004 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253589-A1 | AMINOMETHYLAMIDINE AND METHYLAMIDINE ANTIMICROBIAL COMPOUNDS | BioVersys AG (CH) | 2021-08-19 | — | — | US | disclosed |
| US-10947237-B2 | Antimicrobial compounds and methods of making and using the same | BioVersys AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-10934295-B2 | Antimicrobials and methods of making and using same | BioVersys AG (CH) | 2021-03-02 | — | — | US | disclosed |
| US-20190211018-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | RIB-X PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20180065966-A1 | Antimicrobial Compounds And Methods Of Making And Using The Same | MELINTA THERAPEUTICS, INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934295-B2 | Antimicrobials and methods of making and using same | LPO, MPO, OAT | TSHR 4002/4885 |
| US-20180065966-A1 | Antimicrobial Compounds And Methods Of Making And Using The Same | LPO, MPO, CAT | TSHR 4406/4885 |
| US-20210253589-A1 | AMINOMETHYLAMIDINE AND METHYLAMIDINE ANTIMICROBIAL COMPOUNDS | MTAP, PRMT3, AMPD2 | TSHR 4142/4885 |
| US-20190211018-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | LPO, MPO, OAT | TSHR 4002/4885 |
| US-10947237-B2 | Antimicrobial compounds and methods of making and using the same | LPO, MPO, CAT | TSHR 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.