Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 17/20 | 0.75 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24271572 | 0.85 | BCHE (0.79) | BCHENOX1HPGD | |
| SCHEMBL19939631 | 0.81 | BCHE (0.71) | BCHENOX1 | |
| SCHEMBL17999687 | 0.80 | BCHE (0.59) | BCHELMNAHPGD | |
| SCHEMBL30300622 | 0.80 | BCHE (0.59) | BCHELMNAHPGD | |
| SCHEMBL19939626 | 0.80 | BCHE (0.70) | BCHE | |
| SCHEMBL13295920 | 0.78 | BCHE (0.64) | BCHELMNA | |
| SCHEMBL17999647 | 0.77 | BCHE (0.65) | BCHE | |
| SCHEMBL17999685 | 0.76 | BCHE (0.64) | BCHE | |
| SCHEMBL31366229 | 0.76 | BCHE (0.64) | BCHE | |
| SCHEMBL2762804 | 0.74 | BCHE (0.74) | BCHENOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459910-B2 | Mitochondrial therapeutic agents | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2025-11-04 | — | — | US | disclosed |
| US-20240409521-A1 | MITOCHONDRIAL THERAPEUTIC AGENTS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2024-12-12 | — | — | US | disclosed |
| US-20220081404-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-03-17 | — | — | US | disclosed |
| US-11034662-B2 | Substituted phenothiazines as mitochondrial agents | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-06-15 | — | — | US | disclosed |
| EP-3258938-B1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | UNIV ARIZONA STATE (US) | 2020-12-02 | — | — | EP | disclosed |
| US-20200115355-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-04-16 | — | — | US | disclosed |
| US-10472340-B2 | Substituted phenothiazines as mitochondrial agents | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-11-12 | — | — | US | disclosed |
| US-20180065941-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180065941-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065941-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | GSR, COQ8A, TXNRD2 | BCHE 2853/4885NOX1 356/4885LMNA 1915/4885 |
| US-20200115355-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | GSR, COQ8A, TXNRD2 | BCHE 2853/4885NOX1 356/4885LMNA 1915/4885 |
| US-10472340-B2 | Substituted phenothiazines as mitochondrial agents | GSR, TXN2, PCK2 | BCHE 2881/4885NOX1 315/4885LMNA 1334/4885 |
| US-20240409521-A1 | MITOCHONDRIAL THERAPEUTIC AGENTS | TFAM, TXNRD2, AIFM1 | BCHE 4492/4885NOX1 489/4885LMNA 1579/4885 |
| US-12459910-B2 | Mitochondrial therapeutic agents | TFAM, TXNRD2, AIFM1 | BCHE 4492/4885NOX1 489/4885LMNA 1579/4885 |
| US-11034662-B2 | Substituted phenothiazines as mitochondrial agents | GSR, SQOR, MT-ATP6 | BCHE 3148/4885NOX1 419/4885LMNA 2032/4885 |
| US-20220081404-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | GSR, COQ8A, TXNRD2 | BCHE 2853/4885NOX1 356/4885LMNA 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.