Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944334 | 0.89 | LMNA (0.46) | MAPTKMT2AARALDH1A1POLB | |
| SCHEMBL19944372 | 0.86 | MTNR1A (0.50) | MAPTARMTNR1AMTNR1BPOLB | |
| SCHEMBL19944452 | 0.85 | MTNR1A (0.56) | TSHRALDH1A1MTNR1AMTNR1BPOLB | |
| SCHEMBL19944267 | 0.85 | RXRA (0.43) | MAPTKMT2AARALDH1A1POLB | |
| SCHEMBL19944479 | 0.85 | POLB (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28537147 | 0.84 | TDP1 (0.40) | CYP2C9TSHRMAPTKMT2AAR | |
| SCHEMBL19944473 | 0.84 | LTA4H (0.47) | MAPTARMTNR1AMTNR1BPOLB | |
| SCHEMBL4197201 | 0.84 | MAPT (0.47) | MAPTARMTNR1AMTNR1BPOLB | |
| SCHEMBL28729088 | 0.84 | MTNR1A (0.46) | MAPTARMTNR1AMTNR1BPOLB | |
| SCHEMBL4188595 | 0.84 | MAPT (0.50) | CYP2C9MAPTMTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |