Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944267 | 0.89 | RXRA (0.43) | LMNATDP1KMT2AARALDH1A1 | |
| SCHEMBL19944479 | 0.89 | POLB (0.48) | TDP1POLBAPEX1HTTPLA2G4B | |
| SCHEMBL19944240 | 0.89 | CYP2C9 (0.53) | LMNATDP1KMT2AARALDH1A1 | |
| SCHEMBL19944372 | 0.87 | MTNR1A (0.50) | LMNATDP1ARMAPTPOLB | |
| SCHEMBL19944371 | 0.87 | ALDH1A1 (0.48) | LMNAMEN1KMT2AARALDH1A1 | |
| SCHEMBL28538695 | 0.86 | TDP1 (0.45) | LMNATDP1MEN1CYP1A2KMT2A | |
| SCHEMBL15385984 | 0.86 | MTNR1A (0.43) | LMNATDP1MAPTPOLB | |
| SCHEMBL19944473 | 0.85 | LTA4H (0.47) | LMNAARMAPTPOLBHTT | |
| SCHEMBL4197201 | 0.85 | MAPT (0.47) | LMNATDP1ARMAPTPOLB | |
| SCHEMBL4188595 | 0.85 | MAPT (0.50) | LMNACYP1A2MAPTNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041132-A1 | MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | 广东东阳光药业有限公司 | 2018-03-08 | — | — | WO | disclosed |