SCHEMBL19944267

SCHEMBL19944267

C=C(C)C(=O)OC(COc1ccc(CC)cc1)COc1ccc(CC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
AR P10275 1/20 0.42
MAOB P27338 1/20 0.41
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40
KMT2A Q03164 1/20 0.40
HSP90AA1 P07900 1/20 0.40
LMNA P02545 3/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
HTT P42858 2/20 0.39
APEX1 P27695 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FKBP1A P62942 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19944334 0.89 LMNA (0.46) ARNPC1KMT2ALMNAPOLB
SCHEMBL19944371 0.89 ALDH1A1 (0.48) ARKMT2ALMNAALDH1A1
SCHEMBL19944270 0.86 THRB (0.45) ALDH1A1HPGD
SCHEMBL19944479 0.85 POLB (0.48) POLBHTTAPEX1TDP1
SCHEMBL19944240 0.85 CYP2C9 (0.53) ARKMT2ALMNAPOLBMAPT
SCHEMBL19944470 0.85 LMNA (0.43) MAOBLMNA
SCHEMBL14174342 0.85 MTNR1A (0.43) ARLMNAPOLBMAPT
SCHEMBL9926765 0.85 AR (0.45) ARLMNAPOLBMAPTNPSR1
SCHEMBL19944374 0.83 ADRB2 (0.48) ARLMNAPOLBNPSR1ALDH1A1
SCHEMBL19944474 0.83 MAPK1 (0.48) POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641831-B Monomers, polymers, preparation method and use thereof 东莞东阳光医疗智能器件研发有限公司 2021-09-10 CN disclosed
WO-2018041132-A1 MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF 广东东阳光药业有限公司 2018-03-08 WO disclosed