Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 12/20 | 0.52 |
| ▸ | LOX | P28300 | 11/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19952755 | 1.00 | LOXL2 (0.52) | LOXL2LOXSORT1PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL19952744 | 0.99 | LOXL2 (0.52) | LOXL2LOXSORT1PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL19952840 | 0.99 | LOXL2 (0.52) | LOXL2LOXSORT1PRSS1PRSS2 | |
| SCHEMBL19952750 | 0.94 | LOXL2 (0.54) | LOXL2LOX | |
| SCHEMBL19952710 | 0.94 | LOXL2 (0.53) | LOXL2LOX | |
| Hydrochloric Acid SCHEMBL19952655 | 0.94 | LOXL2 (0.54) | LOXL2LOX | |
| Hydrochloric Acid SCHEMBL19952640 | 0.93 | LOXL2 (0.53) | LOXL2LOX | |
| SCHEMBL21140287 | 0.90 | SORT1 (0.47) | LOXL2LOXSORT1 | |
| SCHEMBL19952732 | 0.87 | ITGB1 (0.47) | LOXL2LOXSORT1LY6K | |
| SCHEMBL19952637 | 0.86 | GIGYF2 (0.46) | LOXL2LOXSORT1LY6K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | disclosed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | LOXL2, LOXL1, LOXL3 | LOXL2 1/4885LOX 5/4885SORT1 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.