Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | GHSR | Q92847 | 4/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960839 | 0.84 | HDAC4 (0.39) | AADATMEN1MAPTKMT2ARIPK1 | |
| SCHEMBL19953499 | 0.84 | FABP5 (0.39) | AADATGRM7MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL19953504 | 0.83 | HDAC4 (0.38) | AADATMEN1MAPTKMT2ARIPK1 | |
| SCHEMBL19953671 | 0.75 | ALDH1A1 (0.39) | AADATMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL19953535 | 0.74 | OPRM1 (0.39) | — | |
| SCHEMBL2467842 | 0.69 | MTNR1A (0.46) | GRM7MEN1KMT2A | |
| SCHEMBL19797799 | 0.69 | MTNR1A (0.46) | GRM7MEN1KMT2A | |
| SCHEMBL19960574 | 0.67 | HDAC4 (0.33) | MEN1MAPTKMT2AGHSRRIPK1 | |
| SCHEMBL19960578 | 0.67 | HDAC4 (0.33) | MEN1MAPTKMT2AGHSRRIPK1 | |
| SCHEMBL19960672 | 0.67 | PYGL (0.37) | MEN1KMT2AGHSRTRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | claimed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |