Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960817 | 0.86 | GRIA1 (0.34) | KMT2AGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL19960818 | 0.81 | PER2 (0.33) | KMT2AOPRM1OPRL1MEN1 | |
| SCHEMBL19960710 | 0.81 | GRM7 (0.41) | MC4RKMT2ATSHRMEN1 | |
| SCHEMBL10063160 | 0.71 | OPRM1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL10063154 | 0.63 | OPRM1 (0.42) | GRIA1GRIA2GRIA3GRIA4OPRM1 | |
| SCHEMBL23034824 | 0.62 | MEN1 (0.50) | KMT2ATSHROPRM1OPRL1MEN1 | |
| SCHEMBL26688764 | 0.60 | GRIA1 (0.37) | KMT2AGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8668032 | 0.59 | MEN1 (0.33) | KMT2ATSHRFFAR4MEN1KDM4E | |
| SCHEMBL30545928 | 0.59 | KDM4E (0.39) | TSHRKDM4E | |
| SCHEMBL28356611 | 0.59 | NOTUM (0.62) | BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |