SCHEMBL19954102

SCHEMBL19954102

CCC(C)/C=C(\C#N)c1nccs1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.40
ALDH1A1 P00352 1/20 0.39
JAK3 P52333 1/20 0.33
HSPA9 P38646 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
FFAR2 O15552 1/20 0.31
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14682592 0.86 FTO (0.42) FTOALDH1A1JAK3HSPA9NPC1
SCHEMBL16533076 0.79 ALDH1A1 (0.47) FTOALDH1A1JAK3HSPA9NPC1
SCHEMBL5141220 0.77 FTO (0.41) FTOALDH1A1JAK3NPC1RAB9A
SCHEMBL7535989 0.74 FTO (0.45) FTOALDH1A1JAK3NPC1RAB9A
SCHEMBL7192578 0.73 FTO (0.42) FTOALDH1A1JAK3NPC1RAB9A
SCHEMBL15657999 0.73 FTO (0.42) FTOALDH1A1JAK3NPC1RAB9A
SCHEMBL15658000 0.73 FTO (0.42) FTOALDH1A1JAK3NPC1RAB9A
SCHEMBL19954111 0.71 RAB9A (0.41) ALDH1A1NPC1RAB9AMAPT
SCHEMBL16532962 0.69 FTO (0.47) FTOALDH1A1JAK3NPC1RAB9A
SCHEMBL7688372 0.68 NPC1 (0.56) FTOALDH1A1JAK3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917260-B2 Compounds with terminal heteroarylcyanovinylene groups and their use in organic solar cells BASF SE (DE) 2018-03-13 US disclosed