SCHEMBL1995649

SCHEMBL1995649

CSCc1cnc(C(F)(F)F)s1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8241659 0.79 FDPS (0.37) SLC6A3
SCHEMBL17263320 0.76 SLC6A3 (0.34) SLC6A3
SCHEMBL129946 0.75 EGLN2 (0.31)
SCHEMBL7769591 0.75 ALDH1A1 (0.34)
SCHEMBL5751006 0.75 SCD (0.34)
SCHEMBL13563819 0.75 EGLN2 (0.31)
SCHEMBL1959957 0.75 EGLN2 (0.31)
SCHEMBL12620049 0.75 EGLN2 (0.31)
SCHEMBL7768127 0.75 EGLN2 (0.31)
SCHEMBL21939963 0.74 MEN1 (0.37) SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2338882-B1 2-((6-(Haloalkyl substituted))pyridin-3-yl)-tetrahydro-1H-1(lamba)4-thien-1-ylidenecyanamide derivatives and related compounds as pesticides and insecticides DOW AGROSCIENCES LLC (US) 2017-06-07 EP disclosed
EP-2338882-B1 2-((6-(Haloalkyl substituted))pyridin-3-yl)-tetrahydro-1H-1(lamba)4-thien-1-ylidenecyanamide derivatives and related compounds as pesticides and insecticides DOW AGROSCIENCES LLC (US) 2017-06-07 EP disclosed
EP-2338885-B1 Insecticidal N-Substituted (2-Substituted-1,3-Thiazol) Alkyl Sulfoximines DOW AGROSCIENCES LLC (US) 2012-10-31 EP disclosed
EP-2057135-B1 INSECTICIDAL N-SUBSTITUTED (2- SUBSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2012-06-13 EP disclosed
US-8188292-B2 Insecticidal N-substituted (heteroaryl)alkyl sulfilimines DOW AGROSCIENCES, LLC (US) 2012-05-29 US disclosed
US-8188292-B2 Insecticidal N-substituted (heteroaryl)alkyl sulfilimines DOW AGROSCIENCES, LLC (US) 2012-05-29 US disclosed
US-8188292-B2 Insecticidal N-substituted (heteroaryl)alkyl sulfilimines DOW AGROSCIENCES, LLC (US) 2012-05-29 US disclosed
US-8183270-B2 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES, LLC (US) 2012-05-22 US disclosed
EP-2338883-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol) alkyl sulfoximines Dow AgroSciences LLC (US) 2011-06-29 EP disclosed
EP-2338884-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol) alkyl sulfoximines Dow AgroSciences LLC (US) 2011-06-29 EP disclosed
EP-2057121-A2 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILIMINES Dow AgroSciences LLC (US) 2009-05-13 EP disclosed
US-20080280915-A1 Insecticidal n-substituted (heteroaryl)alkyl sulfilimines CORTEVA AGRISCIENCE LLC 2008-11-13 US disclosed
US-20080280915-A1 Insecticidal n-substituted (heteroaryl)alkyl sulfilimines CORTEVA AGRISCIENCE LLC 2008-11-13 US disclosed
US-20080280915-A1 Insecticidal n-substituted (heteroaryl)alkyl sulfilimines CORTEVA AGRISCIENCE LLC 2008-11-13 US disclosed
WO-2008030266-A2 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILMINES DOW AGROSCIENCES LLC (US) 2008-03-13 WO disclosed
WO-2008030266-A2 INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILMINES DOW AGROSCIENCES LLC (US) 2008-03-13 WO disclosed
WO-2008027539-A1 INSECTICIDAL N-SUBSTITUTED (2- SUDSTITUTED-1,3-THIAZOL) ALKYL SULFOXIMINES DOW AGROSCIENCES LLC (US) 2008-03-06 WO disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines DOW AGROSCIENCES LLC (US) 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280915-A1 Insecticidal n-substituted (heteroaryl)alkyl sulfilimines AANAT, GNMT, STS SLC6A3 311/4885
US-20080058394-A1 Insecticidal N-substituted (2-substituted-1,3-thiazol)alkyl sulfoximines TST, NIT2, MSL1 SLC6A3 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.