Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1259956 | 0.98 | SIGMAR1 (0.38) | SIGMAR1FDPSCYP3A4ALOX15CASP1 | |
| SCHEMBL5417529 | 0.79 | SIGMAR1 (0.35) | SIGMAR1FDPSCYP3A4ALOX15CASP1 | |
| SCHEMBL17778194 | 0.78 | FDPS (0.39) | SIGMAR1FDPSCYP3A4ALOX15CASP1 | |
| SCHEMBL234864 | 0.78 | CYP3A4 (0.53) | SIGMAR1FDPSCYP3A4ALOX15CASP1 | |
| SCHEMBL19140484 | 0.77 | FDPS (0.40) | SIGMAR1FDPSCYP3A4ALOX15CASP1 | |
| SCHEMBL1691505 | 0.77 | FDPS (0.50) | FDPSCYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL3843060 | 0.76 | SIGMAR1 (0.33) | SIGMAR1FDPSALDH1A1 | |
| SCHEMBL618720 | 0.76 | CYP1A2 (0.31) | CYP3A4 | |
| SCHEMBL12561645 | 0.75 | IDO1 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1POLB | |
| SCHEMBL29443967 | 0.75 | CYP3A4 (0.43) | SIGMAR1FDPSCYP3A4ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213557-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2014-07-31 | — | — | US | claimed |
| EP-2640707-B1 | 5-HALOGENOPYRAZOLECARBOXAMIDES | BAYER IP GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |
| US-9414600-B2 | Active compound combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-08-16 | — | — | US | disclosed |
| US-9375004-B2 | 5-halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140213557-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2014-07-31 | — | — | US | disclosed |
| US-8754009-B2 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
| EP-2043995-B1 | A METHOD FOR PRODUCING ALKENYL NITROBENZOL DERIVATIVES UNBRANCHED IN THE 1-POSITION | BAYER CROPSCIENCE AG (DE) | 2013-01-02 | — | — | EP | disclosed |
| EP-2043995-B1 | A METHOD FOR PRODUCING ALKENYL NITROBENZOL DERIVATIVES UNBRANCHED IN THE 1-POSITION | BAYER CROPSCIENCE AG (DE) | 2013-01-02 | — | — | EP | disclosed |
| US-8071824-B2 | Method for producing alkenylnitrobenzene derivatives unbranched in the 1′-position | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | disclosed |
| US-20100076229-A1 | Method for Producing Alkenylnitrobenzene Derivatives Unbranched in the 1'-Position | BAYER CROPSCIENCE AG (DE) | 2010-03-25 | — | — | US | disclosed |
| EP-2046720-A2 | NITROBENZOL DERIVATIVES AND METHOD FOR PRODUCING SAID 1' ALKYLNITROBENZENES AND ALKYLANILINES | Bayer CropScience Aktiengesellschaft (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008006576-A1 | A METHOD FOR PRODUCING ALKENYL NITROBENZOL DERIVATIVES UNBRANCHED IN THE 1-POSITION | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008006574-A2 | NITROBENZOL DERIVATIVES AND METHOD FOR PRODUCING SAID 1' ALKYLNITROBENZENES AND ALKYLANILINES | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| US-20070004921-A1 | Isopentyl carboxanilides for combating undesired micro-organisms | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20070004921-A1 | Isopentyl carboxanilides for combating undesired micro-organisms | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1562595-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1509225-A1 | METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2004026305-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | ELI LILLY AND COMPANY (US) | 2004-04-01 | — | — | WO | disclosed |
| WO-2003099275-A1 | METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213557-A1 | Active Compound Combinations | AGXT, GLUL, GMNN | SIGMAR1 3314/4885FDPS 833/4885CYP3A4 1609/4885 |
| US-20070004921-A1 | Isopentyl carboxanilides for combating undesired micro-organisms | MLYCD, MRPL21, PGLS | SIGMAR1 418/4885FDPS 207/4885CYP3A4 1462/4885 |
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | CYP3A5, CBR3, HDHD5 | SIGMAR1 3101/4885FDPS 29/4885CYP3A4 20/4885 |
| US-20100076229-A1 | Method for Producing Alkenylnitrobenzene Derivatives Unbranched in the 1'-Position | CYP1B1, AKR7A2, CYP1A1 | SIGMAR1 2019/4885FDPS 276/4885CYP3A4 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.