Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 1.00 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19953384 | 0.99 | LOXL2 (0.98) | LOXL2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19953285 | 0.85 | LOXL2 (0.73) | LOXL2CHEK2 | |
| SCHEMBL19964757 | 0.82 | LOXL2 (1.00) | LOXL2 | |
| SCHEMBL400512 | 0.77 | LOXL2 (0.62) | LOXL2MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL19953219 | 0.75 | LOXL2 (0.60) | LOXL2 | |
| SCHEMBL1850732 | 0.73 | LOXL2 (0.57) | LOXL2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19953274 | 0.72 | LOXL2 (0.65) | LOXL2CYP2C9 | |
| SCHEMBL10214972 | 0.71 | LOXL2 (0.55) | LOXL2MAOAMAOB | |
| SCHEMBL4281599 | 0.70 | GABRP (0.54) | LOXL2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31334070 | 0.70 | GABRA5 (0.67) | LOXL2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |