Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19969383 | 1.00 | HTR7 (0.50) | HTR7HTR6ADORA2BLMNAGAA | |
| SCHEMBL19969377 | 0.99 | ADORA2B (0.50) | HTR7HTR6ADORA2BLMNAGAA | |
| SCHEMBL19969303 | 0.94 | LMNA (0.51) | ADORA2BLMNAGAARXFP1TSHR | |
| SCHEMBL7320325 | 0.86 | TSHR (0.57) | HTR7HTR6ADORA2BLMNARXFP1 | |
| SCHEMBL7313395 | 0.84 | TSHR (0.57) | HTR7HTR6ADORA2BLMNARXFP1 | |
| SCHEMBL19969446 | 0.83 | ADORA2A (0.44) | LMNAGAARXFP1TSHRALDH1A1 | |
| SCHEMBL19969126 | 0.83 | ADORA2A (0.44) | LMNAGAARXFP1TSHRALDH1A1 | |
| SCHEMBL11150353 | 0.82 | TSHR (0.55) | HTR7HTR6ADORA2BLMNARXFP1 | |
| SCHEMBL19969450 | 0.82 | ADORA2A (0.44) | LMNAGAARXFP1TSHRALDH1A1 | |
| SCHEMBL7316547 | 0.80 | ALDH1A1 (0.56) | HTR7HTR6ADORA2BLMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634434-B2 | Bifunctional alpha-synuclein binding agents and uses thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2023-04-25 | — | — | US | disclosed |
| US-20200062782-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2020-02-27 | — | — | US | disclosed |
| WO-2018045464-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062782-A1 | BIFUNCTIONAL ALPHA-SYNUCLEIN BINDING AGENTS AND USES THEREOF | SNCA, PARK7, SYNJ2 | HTR7 2811/4885HTR6 2691/4885ADORA2B 2511/4885 |
| US-11634434-B2 | Bifunctional alpha-synuclein binding agents and uses thereof | SNCA, PARK7, SYNJ2 | HTR7 2811/4885HTR6 2691/4885ADORA2B 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.