Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24063950 | 0.89 | NQO1 (0.39) | PPARACYP1A2CYP3A4HTR2AABCB11 | |
| SCHEMBL17861674 | 0.83 | PPARA (0.49) | PPARACYP1A2CYP3A4HTR2AABCB11 | |
| SCHEMBL1040481 | 0.83 | PPARA (0.51) | PPARACYP1A2CYP3A4HTR2AABCB11 | |
| SCHEMBL11336961 | 0.81 | OPRK1 (0.57) | PPARACYP1A2CYP3A4HTR2AABCB11 | |
| SCHEMBL13418269 | 0.80 | ACHE (0.42) | PPARACYP1A2CYP3A4HTR2AABCB11 | |
| SCHEMBL12942965 | 0.78 | KDM4E (0.33) | PPARACYP1A2CYP3A4HTR2AABCB11 | |
| SCHEMBL3081094 | 0.77 | LTA4H (0.40) | PPARACYP1A2TSHRCYP2C19CYP2D6 | |
| SCHEMBL14706810 | 0.77 | NPC1 (0.56) | MAPTLMNACYP2C9MAPK1SMN1; SMN2 | |
| SCHEMBL15489213 | 0.77 | ALDH1A3 (0.44) | CYP1A2MAPTCYP2C19MEN1KMT2A | |
| SCHEMBL196705 | 0.77 | PPARA (0.57) | PPARACYP1A2CYP3A4HTR2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | OPRM1, OPRL1, OPRD1 | PPARA 506/4885CYP1A2 2067/4885CYP3A4 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.